department of chemistry and biochemistry
 

CHEM4341 : Forensic Chemistry

 

Dr. Eamonn F. Healy

 


Forensic Journals:

  • Forensic Jounals : a comprehemsive listing
  • Click Here for instructions for browsing and searching the Journal of Forensic Sciences

 

TOPIC: Evidence and Bayesian Probability

LECTURE: Evidence and Bayesian Probability

LINKS: The Monty Hall Problem
A Bayesian Primer
Bayes' Theorem and the Law
DNA Evidence and False Positives

Forensics and Statistics

 

TOPIC: Drug Analysis

LECTURE: Extraction, Characterization and Isolation

  • Drug Scheduling : Bell, pages 213-227
  • Drug Chemistry: Bell, pages 267-272
  • Chemical Solubility : Bell, pages 92-101
  • Liquid-Liquid extraction : Bell, pages 102-107
  • Solid-Liquid extraction : Bell, pages 108-11; 116-120; 337-342
             

LECTURE: Presumptive Tests

  • Light & Color: Bell, pages 271-280
  • UV/Vis Spectroscopy: Bell, pages 149-162
  • Marquis test: Bell, pages 282-283
  • Scott test : Bell, pages 289-293
             

LECTURE: Characterization by GC-MS

  • GC and MS: Bell, pages 194-203
  • Mass Spectra : Bell, pages 351-352
  • Gas Chromatographs : Bell, pages 236-237; 438-439
             

CASE STUDY : "Drugs on Money", Anal. Chem., June 1, 2000; pp. 397 A-403 A

LINKS:

  • GC-MS & HPLC
             
  • TOPIC: Statistics I

    LECTURE: Basic Concepts

    • Data: Quality & Certainty : Bell, pages 15-27
    • Hypothesis : G test and t test Bell, pages 27-35
               

    LINKS:

     

    TOPIC: Forensic Toxicology

    LECTURE: Basic Concepts

    • An Overview of Pharmacology : Bell, Chapter 6, pages 239-262

    PRESENTATION OUTLINE

    • Toxicology; including physical, chemical and spectroscopic properties
    • Pathology
    • Pharmacodynamics; icluding affected biochemical pathways
    • Pharmacokinetics; including metabolism and cross-tolerance
    • Forensics; including origin, delivery and detection
    • Treatment

     

    TOPIC
    STUDENT
    DATE
    Ethylene Glycol, Methanol and Isopropanol
    Bea Eamiguel
    Wed., April 20
    Arsenic and Arsenates
    Bich Van Do
    Wed., April 20
    Diquat and Paraquat
    Phenobarbital and Barbiturates
    Crotalid, Elapid and Snake Venoms
    Luis Rivera
    Fri., April 22
    Strychnine
    Blake Howard
    Fri., April 22
    Atropine & Scopolamine
    DDT and Hexachlorophene
    Liliana Garcia
    Mon., April 25
    Parathion and Organophosphates
    Madeline Flores
    Mon., April 25
    Sulfides
    Muscarine & Coprine
    Jude Casasent
    Wed., April 27
    PCP and Ketamine
    Taylor Hays
    Wed., April 27
    Saxitoxin, Tetradotoxins and Batrachotoxins
    Gianna Hall
    Fri, April 29
    Morphine & Synthetic Opiates
    Salicylic Acid and Salicylates
    Amitriptyline and Tricyclics
    Lead
    Katie Tucker
    Fri, April 29
    Mercury
    Caffeine & the Methylxanthines
    Cardiac Glycosides
    Paige Patton
    Fri, April 29

     

    CASE STUDY : "False Cyanide Detection", Anal. Chem., March 1, 2002 / volume 74, issue 5 /pp 134 A-141 A ; "Arsenic Speciation", Anal. Chem., Volume 76, Issue 1
    pp 1 A–40 A.

     

    TOPIC: DNA : Profiling and Fingerprinting

    LECTURE: DNA Basic Concepts

    LECTURE: DNA testing

    LECTURE: STRs and Population Analysis

    • Restriction Fragment Length Polymorphism analysis
    • Variable Number Tandem Repeat analysis
    • Short Tandem Repeat analysis
    • Mitochondrial DNA analysis
    • Population genetics and Hardy-Weinberg equilibrium
    • Allele frequency and the CODIS database
    • Power of Discrimination & Power of Exclusion

    CASE STUDY : "The Forensic Community’s Response to September 11", Anal. Chem., April 1, 2002 / volume 74, issue 7 / pp 190 A-195 A

    TOPIC: Statistics II

    LECTURE: Calibration

    TOPIC: Combustion and Explosion

    LECTURE: Arson and Explosives

    • Thermodynaics and Kinetics of Combustion : Bell, pages 384--407
    • Arson Investigation Bell, pages 432-440.
    • Detonation and Explosion : Bell, pages 413--428
    • Explosives Bell, pages 448-457.

    CASE STUDY : "A Detection of Explosives by Electronic Noses.", Anal. Chem., Volume 75, Issue 5
    pp 81 A–128 A ; "Chemical Analysis of Arson Debris", Anal. Chem., Volume 68 (1996),
    pp 541A